Umkhiqizi onokwethenjelwa

I-Jiangsu Jingye Pharmaceutical Co., Ltd.
isibhengezo_sekhasi

imikhiqizo

(3S)-3-(7-bromo-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propionic acid methyl ester

Incazelo emfushane:


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isingeniso Somkhiqizo

Omqondofana:3-(10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-YLIDENE)-N, N-DIMETHYL-1-PROPANAMINEHYDROCHLORIDE; I-AMTRIPTYLINEHYDROCHLORIDE98+%; AMTRIPTYLINEHYDROCHLORIDESOLUTION; 3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLIDENE)-N, N-DIMETHYL-1-PROPANAMINEHYDROCHLORIDE

Inombolo ye-CAS:308242-23-1

I-Molecular Formula: C20H24ClN

Isisindo se-Molecular:313.86

Inombolo ye-EINECS:208-964-6

a

Isakhiwo

Isicelo:Imithi, abaphakathi, ama-API, ukwakheka ngokwezifiso, amakhemikhali

Ubukhulu:Umthengisi Ongcono Kakhulu, Ikhwalithi Ephezulu, Intengo Encintisanayo, Ukulethwa Okusheshayo, Ukuphendula Ngokushesha

Isebenzisa:I-Antidepressant, esebenza ezimpawu ezihlukahlukene zokucindezeleka zokucindezeleka kanye ne-organic psychosis

Izigaba ezihlobene:I-BiogenicAmineTransportInhibitors; I-BiogenicAmineTransportInhibitorsObesityResearch; I-Neurotransmission; I-Neurotransmission (Ukukhuluphala); Ama-Neurotransmitters; I-Adrenoceptor; Ama-amines; I-Intermediate&FineChemical; Ezemithi

Ukubukeka Isithombe

I-Amitriptyline hydrochloride 2

Izakhiwo

Iphoyinti lokuncibilika 196-197°C
Iphoyinti le-Flash 11 °C
Ukuminyana 1.3134 (isilinganiso esinzima)
Inkomba ye-refractive 1.5490(isilinganiso)
Ukuncibilika H2O; encibilikayo
Ifomu impushana
pKa 9.4(ku-25℃)
PH 4.5~6.0 (10g/l, 25℃)
Umbala okumhlophe kuya kokumhlophe
Ukuncibilika kwamanzi Cishe obala

Ulwazi Lokuphepha

Ikhodi Yesigaba Sezingozi 23/24/25-36/37/38-42/43-63-39/23/24/25-11-50/53-36-22
Izitatimende Zokuphepha 22-26-36/37/39-45-36/37-16-61-60-7
Ukuthuthwa kwezimpahla eziyingozi No UN 2811 6.1/PG 3
I-WGK Germany 3
I-RTECS HO9450000
Izinga lengozi 6.1(b)
Isigaba sokupakisha III
Ikhodi ye-HS 29214990

I-Jingye Imininingwane

Ukucaciswa okukhethekile ngokwezidingo zekhasimende
Ukubukeka I-crystalline emhlophe noma emhlophe, cishe impushana emhlophe
Ukulahlekelwa Ekumisweni 0.5%ubuningi
Iphoyinti lokuncibilika 195-199 ℃
Izinsalela ekushiseni 0.1%ubuningi
Ubumsulwa (HPLC) 98.0%-102.0% (esomisweni)
Amazinga Ekhwalithi Uhlelo lwe-USP36

Ukusetshenziswa Okuphephile

Izinyathelo zokuphepha zokuphatha okuphephile:
Ukuphatha endaweni enomoya omuhle. Gqoka izingubo ezifanele zokuzivikela. Gwema ukuthinta isikhumba namehlo. Gwema ukwakheka kothuli nama-aerosol. Sebenzisa amathuluzi angashiyi izinhlansi. Vimbela umlilo obangelwa umusi wokukhipha i-electrostatic.

Imibandela yokugcina okuphephile, okuhlanganisa noma yikuphi ukungahambisani:
Gcina isitsha sivalwe ngokuqinile endaweni eyomile futhi enomoya omuhle. Izinga lokushisa elinconyiwe lokugcina: 2 - 8 deg C. Gcina endaweni eyomile. I-Amitriptyline hydrochloride.

Izinzuzo Zomkhiqizo

I-Jingye inamasethi angama-86 wama-reactor esewonke, lapho ivolomu ye-reactor yoqweqwe lwawo ingu-69, isuka ku-50 iye ku-3000L. Inombolo yama-reactors angenasici yi-18, isuka ku-50 iye ku-3000L. I-QC ifakwe amakhulu azo zonke izinhlobo zamathuluzi okuhlaziya. Ingakwazi ukuhlangabezana nokukhiqizwa kwezentengiselwano kanye nokuhlaziywa okuphelele komkhiqizo. Lo mkhiqizo ungumkhiqizo osezingeni eliphezulu futhi ungalethwa ngokuya ngezidingo zamakhasimende.

Izinzuzo zenkampani

I-Jingye Pharmaceutical Management and production activities ithobelana ngokuqinile nezidingo ze-GMP, esiza i-Jingye Pharmaceutical ithumele imikhiqizo yayo eYurophu, eMelika naseNingizimu naseMpumalanga Asia. Ngendawo yokukhiqiza eyenziwe yesimanje, amathuluzi okuhlaziya athuthukile nohlelo lwe-EHS oluzwakalayo, i-Jingye Pharmaceutical iqinisekiswe yi-ISO9001, ISO14001 kanye ne-GB/T28001, futhi manje isendleleni eya kumkhiqizi we-GMP Pharmaceuticals Manufacturer.


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