Abaphakathi kwe-Remazolam Benzenesulfonate (CAS No. 308242-23-1)
Omqondofana:(3S)-(7-BroMo-2-oxo-5-pyridin-2-yl-2, 3-dihydro-1H-benzo[e][1,4]diazepin-3-yl) -propionic acid Methylester; I-Methyl3--[(3S)-7-bromo-2-oxo-5-(2-pyridinyl)-2, 3-dihydro-1H-1, 4-benzodiazepin-3-yl]propanoate; (S)-Methyl3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2, 3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate; 3--[(S)-7-bromo-2-oxo-5-pyridin-2-yl-2, 3-dihydro-1H-1, 4-benzodiazepin-3-yl]-propionicacidmethylester.
Inombolo ye-CAS:308242-23-1
I-Molecular Formula:C18H16I-BrN3O3
Isisindo se-Molecular:402.24
Isicelo: Imithi, abaphakathi, ama-API, ukwakheka ngokwezifiso, amakhemikhali
Isebenzisa:Izidakamizwa ze-Remazolam Benzenesulfonate
Isakhiwo
Ubukhulu:Umthengisi Ongcono Kakhulu, Ikhwalithi Ephezulu, Intengo Encintisanayo, Ukulethwa Okusheshayo, Ukuphendula Ngokushesha
Izigaba ezihlobene:Amakhemikhali Amahle
Iphuzu elibilayo | 545.3±50.0 °C(Kubikezelwe) |
Ukuminyana | 1.52±0.1 g/cm3(Kubikezelwe) |
Isimo sesitoreji | Kuvalwe endaweni eyomile, Emazingeni Okushisa Egumbi |
pKa | 11.15±0.70(Kubikezelwe) |
Ukucaciswa okukhethekile ngokwezidingo zekhasimende | |
Ukubukeka | Impushana emhlophe ukuya kokuphuzi |
Amanzi | 1.0% ubuningi |
Isomer | 1.5%ubuningi |
Ubumsulwa | 98.0%iz |
Izinyathelo zokuphepha zokuphatha okuphephile:
Ukuphatha endaweni enomoya omuhle. Gqoka izingubo ezifanele zokuzivikela. Gwema ukuthinta isikhumba namehlo. Gwema ukwakheka kothuli nama-aerosol. Sebenzisa amathuluzi angashiyi izinhlansi. Vimbela umlilo obangelwa umusi wokukhipha i-electrostatic.
Imibandela yokugcina okuphephile, okuhlanganisa noma yikuphi ukungahambisani:
Gcina isitsha sivalwe ngokuqinile endaweni eyomile, epholile futhi enomoya omuhle. Gcina ngaphandle kweziqukathi zokudla noma izinto ezingahambelani.
I-Jingye inamasethi angama-86 wama-reactor esewonke, lapho ivolomu ye-reactor yoqweqwe lwawo ingu-69, isuka ku-50 iye ku-3000L. Inombolo yama-reactors angenasici yi-18, isuka ku-50 iye ku-3000L. I-QC ifakwe amakhulu azo zonke izinhlobo zamathuluzi okuhlaziya. Ingakwazi ukuhlangabezana nokukhiqizwa kwezentengiselwano kanye nokuhlaziywa okuphelele komkhiqizo. Lo mkhiqizo ungumkhiqizo osezingeni eliphezulu futhi ungalethwa ngokuya ngezidingo zamakhasimende.
I-Jiangsu Jingye Pharmaceutical Co., Ltd. phambilini ibiqanjwe ngokuthi i-Jintan Depei Chemical Co., Ltd. eyasungulwa ngo-1994, futhi iphendukela kumkhiqizi wemithi ochwepheshe ngo-2016. Ngemva kweminyaka engamashumi amabili yentuthuko, i-Jingye Pharmaceutical isikhule yaba yingcweti yemithi yokwelapha enemininingwane eminingi. ibhizinisi elihlanganisa i-R&D, ukukhiqiza, ukungenisa nokuthekelisa nezinkampani ezingaphansi ezimbili eziseShanghai naseLianyungang.