I-Moxonidine ne-Moxonidine HCL (I-CAS No.: 75438-57-2)
Omqondofana:4-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-METHOXY-2-METHYL-5-PYRIMIDINAMIN;4-CHLORO-6-METHOXY-2-METHYL-5-(2 -IMIDAZOLIN-2-YL)AMINOPYRIMIDINE HCL;
Inombolo ye-CAS:75438-57-2
I-Molecular Formula:C9H12ClN5O
Isisindo se-Molecular:241.68
Inombolo ye-EINECS:629-833-3
Isicelo:Imithi, abaphakathi, ama-API, ukwakheka ngokwezifiso, amakhemikhali
Isakhiwo
Ubukhulu:Umthengisi Ongcono Kakhulu, Ikhwalithi Ephezulu, Intengo Encintisanayo, Ukulethwa Okusheshayo, Ukuphendula Ngokushesha
Isebenzisa:Izidakamizwa ze-antihypertensive azinayo imiphumela emibi esobala ohlelweni lwezinzwa oluphakathi
Izigaba ezihlobene:Ama-API; I-aromatics; Ama-Heterocycles; Amakhemikhali Aphakathi Namahle; Ezemithi; I-API; I-Cardiovascular APIs
Iphoyinti lokuncibilika | 217-219° (dec) |
Iphuzu elibilayo | 364.7±52.0 °C(Kubikezelwe) |
Ukuminyana | 1.52±0.1 g/cm3(Kubikezelwe) |
Ukuncibilika | Incibilika kancane emanzini, incibilika kancane ku-methanol, incibilika kancane ku-methylene chloride, inyibilika kancane ku-acetonitrile. |
Ifomu | Kucocekile |
pKa | 7.11±0.10(Kubikezelwe) |
Ukuncibilika kwamanzi | 800.3mg/L(izinga lokushisa alishiwongo) |
Ukuthuthwa kwezimpahla eziyingozi No | UN 2811 6.1/PG III |
I-WGK Germany | 3 |
I-RTECS | UV6260290 |
Izinga lengozi | 6.1 |
Isigaba sokupakisha | III |
Ukucaciswa okukhethekile ngokwezidingo zekhasimende | |
Ukubukeka | Okuqinile okumhlophe kuya kokumhlophe |
Ukulahlekelwa Ekumisweni | 1.0%ubuningi |
Izinto Ezihlobene | 1.0%ubuningi |
Izinsalela ekushiseni | 0.1% ubuningi |
Ubumsulwa | 98.0%iz |
Izinyathelo zokuphepha zokuphatha okuphephile:
Ukuphatha endaweni enomoya omuhle. Gqoka izingubo ezifanele zokuzivikela. Gwema ukuthinta isikhumba namehlo. Gwema ukwakheka kothuli nama-aerosol. Sebenzisa amathuluzi angashiyi izinhlansi. Vimbela umlilo obangelwa umusi wokukhipha i-electrostatic.
Imibandela yokugcina okuphephile, okuhlanganisa noma yikuphi ukungahambisani:
Gcina isitsha sivalwe ngokuqinile endaweni eyomile, epholile futhi enomoya omuhle. Gcina ngaphandle kweziqukathi zokudla noma izinto ezingahambelani.
Ithimba le-R&D
Isakhiwo esizimele se-R&D Isikhungo sokuhlola umshayeli esizimele Ithimba Lokucwaninga Lochwepheshe (ochwepheshe aba-4 nonjiniyela abaphezulu aba-5, abanye baneziqu) Imishini yokuhlola yobungcweti i-Jingye isebenza ngokubambisana ne-Beijing zhongguancun life science park, i-Shanghai Organic Chemical Research Institute of Chinese Academy of Sciences, Inyuvesi yaseNanjing , i-Chinese Pharmaceutical University. UJingye uphinde asebenzisane namabhizinisi aphesheya.
Iqembu le-QC
Iba nesakhiwo se-QC esiphrofeshinali amasethi angu-7 e-HPLC, Ngokulandelanayo: I-Agilent LC1260, i-Shimadzu LC2030 njll. . Isethi eyodwa yebhokisi lokuhlola ukuzinza kwezidakamizwa (ukuphila okuphakade), Isethi eyodwa yebhokisi lokuhlola ukuzinza kwezidakamizwa (ukuphila okuphakade) amasethi angu-2 ezidakamizwa zezokwelapha ezipholile ezingu-2-8℃ (I-Haier), Isethi eyodwa yebhokisi lokulondoloza uhlobo lokushisa oluphansi ( Haier) njll.