Izicelo Medical of Dibenzosuberone

I-Dibenzosuberone, i-polycyclic enuka kamnandi eyi-hydrocarbon, izuze ukunakwa okubalulekile emphakathini wesayensi ngenxa yemisebenzi yayo yebhayoloji ethembisayo. Yize yaziwa ngokuyinhloko ngendima yayo njengendawo emaphakathi ekuhlanganiseni kwezinto eziphilayo, i-benzosuberone kanye nokuphuma kwayo kubonise amandla ezinhlelo zokusebenza zezokwelapha ezihlukahlukene. Kulesi sihloko, sizohlola izinzuzo ezingaba khona kanye nokusetshenziswa kwe-benzosuberone emkhakheni wezokwelapha.

Izicelo Zezokwelapha Ezingaba Khona

Izici zokulwa nomdlavuza:

Ucwaningo oluningana lubonise ukuthi i-dibenzosuberone kanye nokuphuma kwayo kubonisa izakhiwo zokulwa nomdlavuza. Lezi zinhlanganisela zikhonjisiwe ukuthi zenza i-apoptosis (ukufa kweseli elihleliwe) kumaseli omdlavuza, zivimbele ukukhula kwesimila, futhi zivimbele ukumetastasis.

Izindlela ezingaphansi kwale miphumela ziyinkimbinkimbi futhi ngokuvamile zihlanganisa ukusebenzisana nezindlela zokubonisa amaselula.

I-Neuroprotective Effects:

I-Dibenzosuberone ibonise imiphumela ye-neuroprotective ezifundweni zangaphambi komtholampilo. Kuye kwaboniswa ukunciphisa ukucindezeleka kwe-oxidative, ukuvuvukala, nokulimala kwe-neuronal okubangelwa ukuphazamiseka okuhlukahlukene kwezinzwa.

Le nhlanganisela ingase inikeze izinzuzo zokwelashwa ezingaba khona ezimweni ezifana nesifo i-Alzheimer's, isifo sikaParkinson, nesifo sohlangothi.

Umsebenzi wokulwa nokuvuvukala:

I-Dibenzosuberone ibonise izakhiwo zokulwa nokuvuvukala, okuyenza ibe ikhandidethi engaba khona ekwelapheni izifo ezivuthayo. Kungase kusize ukunciphisa ukuvuvukala ngokuvimbela ukukhiqizwa kwama-cytokines abangela ukuvuvukala.

Umsebenzi we-Antimicrobial:

Okunye okuphuma ku-dibenzosuberone kubonise umsebenzi we-antimicrobial ngokumelene nohlu lwamagciwane kanye nesikhunta. Lesi sakhiwo singabenza babe usizo ekuthuthukiseni ama-antibiotic amasha nama-antifungal agents.

Izindlela Zokwenza

Izindlela eziqondile i-dibenzosuberone ezenza ngayo imiphumela yazo yebhayoloji aziqondwa ngokugcwele kodwa kucatshangwa ukuthi zibandakanya ukusebenzisana nokuhlosiwe okuhlukahlukene kwamaselula, okuhlanganisa:

Ama-Receptors: I-Dibenzosuberone ingase ibophe futhi isebenze noma ivimbele ama-receptors athile, okuholela ezenzakalweni zokusayina ezingezansi.

Ama-Enzymes: Le nhlanganisela ingase ivimbele noma yenze ama-enzyme athile ahileleke ezinqubweni zamangqamuzana ezifana nokwanda kwamaseli, i-apoptosis, nokuvuvukala.

Ukucindezeleka kwe-oxidative: I-Dibenzosuberone ingase isebenze njenge-antioxidant, ivikela amangqamuzana emonakalweni obangelwa izinhlobo ze-oxygen esebenzayo.

Izinselele kanye Neziqondiso Zesikhathi esizayo

Nakuba izicelo zezokwelapha ezingaba khona ze-dibenzosuberone zithembisa, kunezinselelo ezimbalwa okudingeka zixazululwe ngaphambi kokuba zisetshenziswe njenge-ejenti yokwelapha. Lokhu kubandakanya:

Ubuthi: Ubuthi be- dibenzosuberone kanye nokuphuma kwayo kufanele buhlolwe ngokucophelela ukuze kuqinisekiswe ukuphepha kwakho ekusetshenzisweni komuntu.

Ukutholakala kwe-Bioavailability: Ukwenza ngcono ukutholakala kwe-bioavailability kwe-dibenzosuberone kubalulekile ekuletheni kwayo ngempumelelo ezicutshini eziqondiwe.

Ukwakhiwa kwezidakamizwa: Ukwakhiwa kwezidakamizwa ezifanele zokulethwa kwe-dibenzosuberone kuwumsebenzi onzima.

Isiphetho

I-Dibenzosuberone kanye nokuphuma kwayo kumelela indawo ethembisayo yocwaningo enezicelo ezingase zibe khona ekwelapheni izifo ezihlukahlukene. Kudingeka ucwaningo olwengeziwe ukuze kuqondwe ngokugcwele izindlela zokusebenza zalezi zinhlanganisela futhi kuthuthukiswe ama-ejenti okwelapha aphephile nasebenzayo.